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Archive of Science and Technology(PCU AST) is peer-reviewed double-blind and reputable journal
published by Precious Cornerstone University Ibadan Nigeria. Our mission is to provide a platform for the
exchange of seasoned information on researches and reviews in the domain of science and technology.
We accept high quality research and technical papers, short communications, reviews, book chapters.
Journal Scope: All areas of pure and applied sciences,medical sciences, engineering and technology are covered.
PCU AST CALLS FOR RESEARCH PAPERS
PCUAST Volume 1 Issue 1 June-2020
PREVALENCE OF HERPES SIMPLEX VIRUS-2 IN HIV POSITIVE SUBJECTS ATTENDING UNIVERSITY OF ILORIN TEACHING,HOSPITAL, ILORIN, NIGERIA
Herpes simplex virus type 2(HSV-2) is one of the major causes of anogenital sores in humans. This study aims to determine the seroprevalence of HSV 2 among HIV positive subjects attending the Highly Active Antiretroviral Therapy (HAART) clinic of the University of Ilorin Teaching Hospital, Ilorin, Nigeria.
A total of 200 blood samples were collected from consenting adults and were analysed for HSV-2 antibodies using ELISA. Socio-demographic data, socio-economic factors, behavioral characteristics and the health status of the subjects were obtained using the administered questionnaire.
Results revealed that a seroprevalence of 49.5% (99/200) was obtained for subjects positive for IgM antibodies to the virus. Of the positive subjects, 67 (33.5%) were females while 32 (16.0%) were males (P=0.102). Subjects who were in the age range of 31-40 had the highest seropositivity while those in the age range of 61-70 had the lowest (p=0.002) High seropositivity was noticed with subjects residing in urban areas, 87 (43.5%) compared to 12 (6.0%) for rural dwellers (p=0.047). Trends of increasing seropositivity were observed in this order: divorced, widowed, separated, single and married (p=0.000). The group of subjects with tertiary education had the highest valueHSV-2 prevalence (p=0.001) while subjects by occupational status reveals that the self employed/business people had the highest prevalence of 57(28.5%) at p=0.045. Among the self-employed, traders 49 (24.5%) ranked highest at p=0.001. Respondents that reported yes to the use of condom and that without an answer was associated with the acquisition of the virus. (p=0.000). Similarly, there was significance in relation to subjects that used condoms all the time and those that gave no answer to the use of condom to acquiring the virus(p=0.003)
This study concludes that most of the infected subjects were asymptomatic to HSV-2, Therefore strict adherence to hygiene and safe-sex practice is advocated.
Authors: Ige Itohan Mercy
Kolawole Olatunji Matthew
Keywords: HSV-2, HIV, Seroprevalence, HAART clinic
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